PKD a letter from Dr Leslie Lyons

January 29, 2014

Please feel free to crosspost

Letter from Dr. Leslie Lyons:

Hello Breeders,

Our Feline Genetics laboratory has moved to the University of Missouri, which is much closer to an interested drug company and a strong team of polycystic kidney disease (PKD) researchers at the University of Kansas.  The group in Kansas studies humans.  Like cats, humans have NO therapies for PKD.  We will be working with Dr. David Biller again – who documented the condition and is our expert radiologist, and also researchers at the University of Kansas.

We are now starting interactions to develop drug trials for cats (and humans) and I need your help to develop a network of cooperative and interested breeders to support some studies on PKD.  Any cats at risk for PKD can participate, including but not limited to: Persians, Exotics, Chartreux, British Shorthair, Selkirk Rex, Scottish Folds and American Shorthairs.

I need to develop an e-mail list of interested breeders – potentially those who can drive to the University of Missouri or Kansas State – for a day trip.

We may be doing ultrasound screening clinics and perhaps asking for blood and or urine samples from affected and control cats.  If a cat is dying and has PKD – we would want the cat for a necropsy.  We will be providing other incentives, such as free genetic testing.

Most of the things we do would not be of cost to the breeder and we are not proposing anything invasive to the cats.  Your cats may qualify for a drug trial.

Can you help me form a network of interested breeders that we can call upon for PKD studies?


Best regards



Leslie A. Lyons, PhD

Gilbreath-McLorn Endowed Professor of Comparative Medicine

Department of Veterinary Medicine & Surgery

College of Veterinary Medicine

E109 Vet Med Building, 1600 E. Rollins St.

University of Missouri – Columbia

Columbia, MO 65211  Phone: 01 573 882 9777Website: felinegenetics.missouri.eduLab: 01 573 884 2287 Lab e-mail: felinegenome@missouri.eduProfessor Emerita – University of California – Davis